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Psychedex
Facts label

Salvia divinorum Facts

Hallucinogen; Salvinorin; Kappa-opioid receptor agonist

Dose and duration

No dose or duration recorded for any route.

Body and dependence

Acute toxicity
Low
Chronic toxicity
Negligible
Physical dependence
None
Psychological dependence
Negligible
Withdrawal
None recorded
Compulsive redosing
Negligible

Tolerance

Builds
Rapid
Fully resets after
Not recorded

Effectslikely at a common dose

Perception
Depth perception distortion; Holotropic state; Perspective distortion; Proprioceptive distortion; Sensory deprivation; Spatial disorientation; Vestibular distortion; Visual morphing; +13 possible, including Visual acuity suppression, Visual haze / noise
Body
Body schema distortion; Dizziness; Motor control impairment; Sedation; +11 possible, including Nystagmus (eye wobbles), Trembling
Thinking
Cognitive impairment; Confusion; Decision impairment; Focus suppression; Information processing suppression; Memory fragmentation; Memory suppression; Novelty enhancement; Thought disorganization; +6 possible, including Analysis suppression, Cognitive dysphoria, Language suppression
Feeling
none likely · 4 possible, including Anxiety, Dysphoria, Emotional lability
Self
Communication suppression; Depersonalization; Derealization; Social disconnection; +2 possible
Time
Temporal disorientation; Time alteration; +2 possible
Transpersonal
none likely · 1 possible

Who shouldn't take it

Absolute
Psychotic disorders
Relative
Hepatic impairment; Pregnancy and breastfeeding; Adolescence; Concurrent CYP2D6 or CYP2E1 inhibitors; Unsupervised setting or fall-risk environment

Combinations60 recorded

Dangerous (35)
5-HTP, Tryptophan; Alpha-2 adrenergic receptor antagonist; Amphetamines; Anticholinergics; Antipsychotics; Atypical antipsychotics; Buspirone; Cannabis; Cannabis, THC; CBD; Dopamine agonists; DXM; Ephedrine, Pseudoephedrine; GHB, Baclofen; GHB, GBL; Ketamine, DXM, PCP; Lithium; Local anesthetics; MAOIs; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; NSAIDs; and 11 more, see full page
Caution (17)
See full page: psychedex.org/substances/salvia-divinorum
Not graded (8)
Not listed never means safe.

Seek help immediately if

No emergency profile is recorded for this substance. Not recorded never means no risk.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/salvia-divinorum · Version r2 · Not medical adviceValues as of
On the printout