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Psychedex
Facts label

Poppers Facts

Depressant; Inhalant; Popper; Nitric oxide donor

Dose and durationby route · individual sensitivity varies

Inhaled

No dose recorded for this route. The timings are not a dose guide.

Starts in 10 – 15 secLasts 2 – 5 minAfter-effects 5 – 30 min

Body and dependence

Acute toxicity
Moderate
Chronic toxicity
Moderate
Physical dependence
None
Psychological dependence
Low
Withdrawal
None recorded
Compulsive redosing
Low

Tolerance

Builds
Rapid
Fully resets after
Not recorded
Carries over to
nitroglycerin; isosorbide dinitrate; isosorbide mononitrate

Effectslikely at a common dose

Perception
none likely · 6 possible, including Vestibular distortion, Visual haze / noise
Body
Abnormal heartbeat; Muscle relaxation; Sexual arousal enhancement; Dizziness; Body high; +11 possible, including Headache, Heart rate perception changes, Temperature dysregulation
Thinking
none likely · 4 possible, including Cognitive impairment, Compulsive redosing urge
Feeling
none likely · 1 possible
Self
none likely · 2 possible
Time
none likely · 1 possible

Who shouldn't take it

Absolute
PDE5 inhibitor use (sildenafil, tadalafil, vardenafil); Severe hypotension or hemodynamic instability
Relative
Severe cardiovascular disease; Glucose-6-phosphate dehydrogenase (G6PD) deficiency; Anemia or reduced oxygen-carrying capacity; Glaucoma

Combinations60 recorded

Dangerous (14)
Clonidine, Guanfacine; Amphetamines; Antipsychotics; Atypical antipsychotics; Benzodiazepines, Barbiturates; GHB, Baclofen; GHB, GBL; Ibogaine; Local anesthetics; NDRIs (Wellbutrin); NRIs; SSRIs; Stimulants; Salvia, Ibogaine
Caution (38)
See full page: psychedex.org/substances/poppers
Not graded (8)
Not listed never means safe.

Seek help immediately if

No emergency profile is recorded for this substance. Not recorded never means no risk.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/poppers · Version r1 · Not medical adviceValues as of
On the printout