PCP Facts
Dissociative;
Dose and durationby route · individual sensitivity varies
Oral(mg)
Threshold< 2 mgLight3 – 7 mgCommon7 – 12 mgStrong12 – 20 mgHeavy20+ mg
Starts in 20 – 60 minLasts 4 – 8 hoursAfter-effects 12 – 48 hours
Also recorded: Smoked · Insufflated. See full page: psychedex.org/substances/pcp
Body and dependence
- Acute toxicity
- High
- Chronic toxicity
- High
- Physical dependence
- Low
- Psychological dependence
- Moderate
- Withdrawal
- Mild
- Compulsive redosing
- Moderate
Tolerance
- Builds
- Moderate
- Fully resets after
- Not recorded
- Carries over to
- ketamine;
dextromethorphan; MK-801; methoxetamine
Effectslikely at a common dose
- Perception
- Proprioceptive distortion;
Sensory deprivation; Spatial disorientation; Vestibular distortion; +12 possible, including Double vision, Visual acuity suppression, Visual haze / noise - Body
- Body schema distortion;
Motor control impairment; Nystagmus (eye wobbles); Pain suppression; +28 possible, including Dizziness, Temperature dysregulation, Vasoconstriction - Thinking
- Cognitive impairment;
Confusion; Decision impairment; Information processing suppression; Memory fragmentation; Memory suppression; Thought disorganization; +15 possible, including Analysis suppression, Language suppression, Compulsive redosing urge - Feeling
- none likely · 11 possible, including Paranoia, Anxiety, Dysphoria
- Self
- Depersonalization;
Derealization; +7 possible, including Communication suppression, Social disconnection, Craving - Time
- Temporal disorientation;
+2 possible - Awareness
- none likely · 1 possible
Who shouldn't take it
Absolute
Hypertension; Epilepsy; Psychotic disorders; Renal impairment; Pregnancy
Relative
Bipolar disorder; Hepatic impairment
Combinations68 recorded
Lethal (9)
5-MeO-DALT; 5-MeO-DiPT; 5-MeO-DMT; 5-MeO-MiPT; Dextromethorphan; GHB, GBL; Ibogaine; Tramadol; αMT
Dangerous (41)
Benzodiazepines; Buprenorphine, Kratom; Ephedrine, Pseudoephedrine; MDMA, Amphetamines; Naltrexone; NDRIs (Wellbutrin); NRIs; NSAIDs; Opioids; THC; 5-HTP, Tryptophan; Alpha-2 adrenergic receptor antagonist; Amphetamines; Anticholinergics; Antihistamines; Atypical antipsychotics; Benzodiazepines, Barbiturates; Buspirone; Caffeine; Cannabis; Cannabis, THC; CBD; Dopamine agonists; DXM; and 17 more, see full page
Caution (15)
See full page: psychedex.org/substances/pcp
Not graded (3)
Not listed never means safe.
Seek help immediately if
- Severe disorientation; unable to move or speak (deep dissociation / "k-hole")
- Complete loss of coordination — cannot stand or walk safely
- Vomiting while incapacitated (choking / aspiration risk)
- Very high blood pressure; fast heart rate
- Slow or shallow breathing at high doses (especially mixed with depressants)
- Unconsciousness; rarely, seizures
What to do
- Move them somewhere safe, away from stairs, water, roads, and sharp edges — they cannot protect themselves
- Place in the recovery position if vomiting or unconscious (aspiration is a key risk)
- Stay with them and reassure calmly; keep the environment quiet
- If breathing is slow/shallow or they are unresponsive, call emergency services
- Do not let them wander; do not leave them alone
- Be ready to give rescue breaths / CPR
Effects wear off with time in a safe, monitored setting. The main dangers are physical injury and aspiration while incapacitated, and respiratory depression when combined with other depressants — not the dissociation itself.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/pcp · Version r1 · Not medical adviceValues as of