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Psychedex
Facts label

Nitrous Facts

Dissociative; Depressant; Inorganic molecule; NMDA receptor antagonist

Dose and durationby route · individual sensitivity varies

Inhaled(g)
Threshold< 4 gLight4 – 8 gCommon8 – 16 gStrong16 – 24 gHeavy24+ g

Starts in 5 – 10 secLasts 1 – 5 minAfter-effects 5 – 15 min

Body and dependence

Acute toxicity
Low
Chronic toxicity
High
Physical dependence
Negligible
Psychological dependence
Low
Withdrawal
None recorded
Compulsive redosing
Moderate

Tolerance

Builds
Moderate
Fully resets after
10 days

Effectslikely at a common dose

Perception
none likely · 11 possible, including Spatial disorientation, Vestibular distortion, Visual acuity suppression
Body
Spontaneous body sensations; Dizziness; Motor control impairment; Bodily lightness; Body high; Pain suppression; Tingling / electric sensations; Vibrations / buzzing; +11 possible, including Headache, Nystagmus (eye wobbles), Nausea
Thinking
Cognitive impairment; Cognitive euphoria; +15 possible, including Analysis suppression, Memory suppression, Confusion
Feeling
Anxiety suppression; Euphoria; +1 possible
Self
none likely · 6 possible, including Derealization, Depersonalization, Communication suppression
Time
Time alteration; +2 possible, including Temporal disorientation

Who shouldn't take it

Absolute
Pneumothorax; Vitamin B12 deficiency; Bowel obstruction; Middle ear disease; Recent ophthalmic surgery with intraocular gas
Relative
Pre-existing peripheral neuropathy or myelopathy; First trimester pregnancy

Combinations61 recorded

Lethal (1)
GHB, GBL
Dangerous (29)
Benzodiazepines; Benzodiazepines, Barbiturates; Buprenorphine, Kratom; GHB, Baclofen; Naltrexone; NSAIDs; Opioids; THC; Anticholinergics; Antihistamines; Antipsychotics; Clonidine, Guanfacine; Dopamine agonists; Gabapentin, Pregabalin; Ibogaine; Ketamine, DXM, PCP; Lithium; Local anesthetics; MAOIs; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; Psychedelics; and 5 more, see full page
Caution (25)
See full page: psychedex.org/substances/nitrous
Not graded (6)
Not listed never means safe.

Seek help immediately if

No emergency profile is recorded for this substance. Not recorded never means no risk.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/nitrous · Version r1 · Not medical adviceValues as of
On the printout