Nicotine Facts
Stimulant;
Dose and durationby route · individual sensitivity varies
Oral
No dose recorded for this route. The timings are not a dose guide.
Starts in 15 – 30 minLasts 2 – 4 hoursAfter-effects 1 – 2 hours
Also recorded: Buccal · Smoked · Transdermal. See full page: psychedex.org/substances/nicotine
Body and dependence
- Acute toxicity
- Moderate
- Chronic toxicity
- High
- Physical dependence
- High
- Psychological dependence
- High
- Withdrawal
- Moderate
- Compulsive redosing
- High
Tolerance
- Builds
- Rapid
- Fully resets after
- 10 days
- Carries over to
- cytisine;
varenicline
Effectslikely at a common dose
- Perception
- none likely · 3 possible
- Body
- Stimulation;
Vasoconstriction; Wakefulness; +15 possible, including Abnormal heartbeat, Nausea, Dizziness - Thinking
- Compulsive redosing urge;
+10 possible - Feeling
- none likely · 3 possible, including Anxiety
- Self
- Craving;
+4 possible - Awareness
- Sustained attention (vicara);
+2 possible
Who shouldn't take it
Absolute
Pheochromocytoma;
Relative
Coronary artery disease;
Combinations60 recorded
Lethal (1)
MAOIs
Dangerous (26)
Anticholinergics;
Caution (30)
See full page: psychedex.org/substances/nicotine
Not graded (3)
Not listed never means safe.
Seek help immediately if
No emergency profile is recorded for this substance. Not recorded never means no risk.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/nicotine · Version r1 · Not medical adviceValues as of