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Myristicin Facts

Deliriant; Phenylpropene; Monoamine oxidase inhibitor

Dose and durationby route · individual sensitivity varies

Oral(mg)
Thresholdnot recordedLight50 – 200 mgCommon200 – 500 mgStrong500 – 800 mgHeavy800+ mg

Starts in 3 – 8 hoursLasts 12 – 72 hoursAfter-effects 24 – 72 hours

Body and dependence

Acute toxicity
High
Chronic toxicity
High
Physical dependence
None
Psychological dependence
None
Withdrawal
Not assessed
Compulsive redosing
Not assessed

Tolerance

Not recorded.

Effectslikely at a common dose

Perception
Visual drifting; Color enhancement; +8 possible, including Visual acuity suppression
Body
none likely · 18 possible, including Dehydration sensation, Dizziness, Nausea
Thinking
none likely · 10 possible, including Confusion, Analysis suppression, Language suppression
Feeling
none likely · 4 possible, including Anxiety
Self
none likely · 1 possible, including Depersonalization

Who shouldn't take it

None recorded. Not listed never means safe to take.

Combinations60 recorded

Lethal (6)
Amphetamines; MDMA, Amphetamines; MDMA, MDA; Psychedelics; SNRIs; Stimulants
Dangerous (28)
5-HTP, Tryptophan; Alpha-2 adrenergic receptor antagonist; Buspirone; Ephedrine, Pseudoephedrine; Local anesthetics; NDRIs (Wellbutrin); NRIs; Opioids; SSRIs; Antihistamines; Antipsychotics; Benzodiazepines, Barbiturates; Caffeine; Cannabis; Clonidine, Guanfacine; Dopamine agonists; DXM; GHB, Baclofen; GHB, GBL; Ibogaine; Ketamine, DXM, PCP; L-Tyrosine; Naltrexone; NSAIDs; and 4 more, see full page
Caution (20)
See full page: psychedex.org/substances/myristicin
Not graded (6)
Not listed never means safe.

Seek help immediately if

Deliriants are genuinely dangerous — treat any strong reaction as a medical emergency.

  • True delirium — confused, disoriented, doesn't know what's real or recognize people/danger
  • Vivid, frightening hallucinations; agitation or aggression
  • Hot, flushed, dry skin and high body temperature
  • Dilated pupils; blurred vision
  • Fast heartbeat; inability to urinate
  • Seizures; unconsciousness

What to do

  1. Call emergency services — deliriant poisoning (especially datura / belladonna) can be life-threatening
  2. Keep them physically safe — they may not know what they're doing and can badly injure themselves; remove hazards and stay with them
  3. Do not leave them alone; do not try to reason them out of it — they are delirious
  4. If overheating, cool the body
  5. Recovery position if drowsy, vomiting, or unconscious; be ready for rescue breaths / CPR

Deliriant effects are long (many hours to more than a day) and the person is not safe or in control throughout. The main dangers are self-injury during delirium, overheating, and — for potent anticholinergics like datura — cardiac and central-nervous-system toxicity. Medical monitoring is often needed.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

Version r1 · Not medical advice
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