Modafinil Facts
Stimulant;
Dose and durationby route · individual sensitivity varies
Oral(mg)
Threshold< 25 mgLight50 – 100 mgCommon100 – 200 mgStrong200 – 400 mgHeavy400+ mg
Starts in 20 – 60 minLasts 5 – 10 hoursAfter-effects 6 – 16 hours
Body and dependence
- Acute toxicity
- Low
- Chronic toxicity
- Low
- Physical dependence
- None
- Psychological dependence
- Low
- Withdrawal
- None recorded
- Compulsive redosing
- Negligible
Tolerance
- Builds
- Slow
- Fully resets after
- Not recorded
- Carries over to
- armodafinil;
adrafinil
Effectslikely at a common dose
- Perception
- none likely · 2 possible
- Body
- Stimulation;
Wakefulness; +6 possible, including Insomnia, Dehydration sensation, Headache - Thinking
- none likely · 7 possible
- Feeling
- none likely · 1 possible, including Anxiety
- Awareness
- Sustained attention (vicara);
+1 possible
Who shouldn't take it
Absolute
Known hypersensitivity to modafinil or armodafinil; Pregnancy
Relative
Pre-existing cardiovascular disease; Psychotic disorders; Bipolar disorder; Severe hepatic impairment; Renal insufficiency; Pediatric use
Combinations62 recorded
Lethal (2)
Ibogaine; Tramadol
Dangerous (29)
Alpha-2 adrenergic receptor antagonist; Amphetamines; Benzodiazepines, Barbiturates; Ephedrine, Pseudoephedrine; Local anesthetics; MAOIs; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; Opioids; SSRIs; Stimulants; Anticholinergics; Antipsychotics; Buspirone; Caffeine; Dopamine agonists; DXM; GHB, Baclofen; GHB, GBL; Ketamine, DXM, PCP; Lithium; NSAIDs; and 5 more, see full page
Caution (28)
See full page: psychedex.org/substances/modafinil
Not graded (3)
Not listed never means safe.
Seek help immediately if
No emergency profile is recorded for this substance. Not recorded never means no risk.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/modafinil · Version r1 · Not medical adviceValues as of