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Psychedex
Facts label

HHC Facts

Cannabinoid; Cannabinoid; Cannabinoid CB1 receptor partial agonist

Dose and durationby route · individual sensitivity varies

Oral(mg)
Threshold< 2.5 mgLight5 – 10 mgCommon10 – 25 mgStrong25 – 50 mgHeavy50+ mg

Starts in 30 – 90 minLasts 4 – 8 hoursAfter-effects 2 – 12 hours

Also recorded: Vaporized. See full page: psychedex.org/substances/hhc

Body and dependence

Acute toxicity
Low
Chronic toxicity
Low
Physical dependence
Low
Psychological dependence
Low
Withdrawal
Mild
Compulsive redosing
Low

Tolerance

Builds
Moderate
Fully resets after
21 days
Carries over to
Δ⁹-THC; Δ⁸-THC; Other CB1 agonists

Effectslikely at a common dose

Perception
none likely · 15 possible, including Spatial disorientation, Visual haze / noise
Body
Body high; +19 possible, including Heart rate perception changes, Motor control impairment, Dizziness
Thinking
none likely · 29 possible, including Memory suppression, Cognitive impairment, Decision impairment
Feeling
none likely · 6 possible, including Anxiety, Emotional lability, Paranoia
Self
none likely · 6 possible, including Communication suppression, Craving, Derealization
Time
none likely · 3 possible, including Temporal disorientation
Awareness
none likely · 1 possible

Who shouldn't take it

Absolute
Psychotic disorders; Pregnancy and lactation
Relative
Cardiovascular disease; Anxiety disorders; Cannabis use disorder; Hepatic impairment; Adolescence; Concurrent CYP2C9/3A4 substrate medications

Combinations60 recorded

Dangerous (11)
Ketamine, DXM, PCP; Opioids; GHB, Baclofen; GHB, GBL; Ibogaine; Local anesthetics; MAOIs; NDRIs (Wellbutrin); Salvia, Ibogaine; SNRIs; Synthetic cannabinoids
Caution (33)
See full page: psychedex.org/substances/hhc
Not graded (16)
Not listed never means safe.

Seek help immediately if

Natural cannabis rarely causes a medical emergency — "greening out" is: pale/sweaty skin, dizziness, nausea or vomiting, anxiety or panic, rapid heartbeat, feeling faint — and usually passes with rest.

Seek emergency help for these — far more likely with synthetic cannabinoids ("spice" / K2):

  • Seizures
  • Severe chest pain; very fast or irregular heartbeat
  • Unresponsiveness or extreme drowsiness
  • Severe agitation, aggression, or psychosis
  • Repeated vomiting; difficulty breathing

What to do

  1. Sit or lie them down somewhere calm, cool, and quiet
  2. Reassure them — cannabis panic and "greening out" pass with time
  3. Offer sips of water; a little sugar can help if they feel faint
  4. Recovery position if nauseated, drowsy, or vomiting
  5. Stay with them and monitor
  6. For seizures, chest pain, unresponsiveness, or severe agitation, call emergency services

Natural cannabis "greening out" resolves with rest, calm, and time, with no lasting harm. Synthetic cannabinoids are unpredictable and can cause seizures, cardiac events, kidney injury, and severe agitation that needs emergency care.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/hhc · Version r1 · Not medical adviceValues as of
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