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Entity
Eszopiclone
PSX-0182
Open Beta
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Common namesLunesta, Eszop
Substitutive name(+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate
PsychoactiveDepressant
ChemicalCyclopyrrolone
PharmacologicalGABA-A receptor positive allosteric modulator
+1 more
GABA systemThreshold
< 0.5 mg
Light
1 – 1.5 mg
Common
2 – 3 mg
Strong
4 – 5 mg
Heavy
6+ mg
Onset
10 – 20 min
Peak
30 – 90 min
Total:6 – 8 hours
minlowmodhigh
Acute
Chronic
Physical
Psych.
Withdrawalnot assessed
Buildupwithin a couple of weeks of daily use
Full reset10.5 days
Cross-tol.benzodiazepines
Dosage varies by body weight, tolerance & metabolism · Not medical advice · Terms
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Eszopiclone
Effects (24)
Dependence
extremely physically and psychologically addictive
experience reports
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First-person accounts of subjective effects, timing, and outcomes — submitted for harm reduction.
Last updated Mar 17, 2026Report an issue