Ephylone Facts
Stimulant;
Dose and durationby route · individual sensitivity varies
Oral(mg)
Threshold< 5 mgLight10 – 20 mgCommon20 – 40 mgStrong40 – 80 mgHeavynot recorded
Starts in 15 – 30 minLasts 4 – 8 hoursAfter-effects 6 – 24 hours
Body and dependence
- Acute toxicity
- High
- Chronic toxicity
- Moderate
- Physical dependence
- Moderate
- Psychological dependence
- High
- Withdrawal
- Moderate
- Compulsive redosing
- High
Tolerance
- Builds
- Moderate
- Fully resets after
- Not recorded
- Carries over to
- cocaine;
amphetamine; MDPV; methylone; mephedrone; eutylone
Effectslikely at a common dose
- Perception
- none likely · 6 possible
- Body
- Appetite suppression;
Body high; Insomnia; Physical fatigue; Stimulation; Wakefulness; +22 possible, including Heart rate perception changes, Vasoconstriction, Bruxism - Thinking
- none likely · 26 possible, including Compulsive redosing urge, Decision impairment, Cognitive dysphoria
- Feeling
- Emotional enhancement;
Euphoria; +11 possible, including Anxiety, Anhedonia, Depression - Self
- none likely · 9 possible, including Craving, Compulsive repetitive behavior
- Awareness
- none likely · 1 possible
Who shouldn't take it
Absolute
Pre-existing cardiovascular disease; Pregnancy and lactation; MAO inhibitors
Relative
Seizure disorders; Hepatic impairment; Hyperthermia-prone conditions; Concurrent serotonergic medication
Combinations61 recorded
Lethal (2)
MAOIs; Tramadol
Dangerous (33)
Alpha-2 adrenergic receptor antagonist; Anticholinergics; Atypical antipsychotics; Caffeine; Dopamine agonists; Ephedrine, Pseudoephedrine; Local anesthetics; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; Opioids; SNRIs; SSRIs; Stimulants; 5-HTP, Tryptophan; Antihistamines; Antipsychotics; Buspirone; Clonidine, Guanfacine; DXM; GHB, Baclofen; GHB, GBL; Ibogaine; and 9 more, see full page
Caution (23)
See full page: psychedex.org/substances/ephylone
Not graded (3)
Not listed never means safe.
Seek help immediately if
- Overheating / very high body temperature — heavy sweating, then hot dry skin (the leading cause of MDMA deaths, worse when dancing in hot venues)
- Muscle rigidity, jaw clenching, tremor, or twitching (possible serotonin syndrome)
- Fast, pounding heartbeat; chest pain
- Agitation, confusion; seizures
- Hyponatremia (water intoxication) — headache, confusion, drowsiness, vomiting, and seizures from drinking too much water
- Nausea/vomiting; collapse or unconsciousness
What to do
- Move them somewhere cool and help them cool down — overheating is the main danger
- Sip water to stay hydrated but DO NOT overdrink — roughly a cup (250 ml) per hour if active; too much water can be deadly (hyponatremia)
- Get them to rest and stop dancing
- For overheating, seizures, chest pain, muscle rigidity/tremor, confusion, or unresponsiveness, call emergency services
- Recovery position if drowsy or vomiting; stay with them
- Be ready to give rescue breaths / CPR
Most resolve with cooling, rest, sensible hydration, and time. The life-threatening dangers are hyperthermia, serotonin syndrome, and hyponatremia (too much water) — each a medical emergency, not something to wait out.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/ephylone · Version r1 · Not medical adviceValues as of