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Psychedex
Facts label

Dextroamphetamine Facts

Stimulant; Substituted amphetamine; Dopamine releasing agent

Dose and durationby route · individual sensitivity varies

Oral(mg)
Threshold< 3.75 mgLight3.75 – 10 mgCommon10 – 16 mgStrong16 – 30 mgHeavy30+ mg

Starts in 15 – 30 minLasts 6 – 8 hoursAfter-effects 3 – 6 hours

Also recorded: Insufflated. See full page: psychedex.org/substances/dextroamphetamine

Body and dependence

Acute toxicity
Moderate
Chronic toxicity
Moderate
Physical dependence
Low
Psychological dependence
High
Withdrawal
Moderate
Compulsive redosing
Moderate

Tolerance

Builds
Moderate
Fully resets after
14 days
Carries over to
methamphetamine; lisdexamfetamine; mixed amphetamine salts; methylphenidate

Effectslikely at a common dose

Perception
Dreaming suppression; +3 possible
Body
Appetite suppression; Dry mouth; Insomnia; Physical fatigue; Pupil dilation; Stimulation; Vasoconstriction; Wakefulness; +20 possible, including Heart rate perception changes, Bruxism, Dehydration sensation
Thinking
Cognitive euphoria; +23 possible, including Compulsive redosing urge, Cognitive dysphoria, Thought loops
Feeling
Euphoria; +8 possible, including Anxiety, Dysphoria, Anhedonia
Self
none likely · 9 possible, including Craving, Ego inflation
Time
none likely · 2 possible
Awareness
One-pointedness (ekaggata); Sustained attention (vicara); +1 possible

Who shouldn't take it

Absolute
Symptomatic cardiovascular disease; Moderate-to-severe hypertension; Hyperthyroidism; MAOI use within 14 days; Glaucoma
Relative
Psychotic disorders; Bipolar disorder; Pregnancy

Combinations61 recorded

Lethal (3)
Ibogaine; MAOIs; Tramadol
Dangerous (33)
Anticholinergics; Atypical antipsychotics; Benzodiazepines, Barbiturates; Caffeine; Dopamine agonists; Ephedrine, Pseudoephedrine; Local anesthetics; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; Opioids; Psychedelics; SNRIs; SSRIs; Stimulants; 5-HTP, Tryptophan; Alpha-2 adrenergic receptor antagonist; Antihistamines; Antipsychotics; Buspirone; Clonidine, Guanfacine; DXM; GHB, Baclofen; and 9 more, see full page
Caution (22)
See full page: psychedex.org/substances/dextroamphetamine
Not graded (3)
Not listed never means safe.

Seek help immediately if

  • Chest pain; racing, pounding, or irregular heartbeat
  • Very high body temperature; heavy sweating; hot, flushed skin
  • Severe agitation, paranoia, panic, or confusion
  • Severe headache; muscle rigidity or twitching
  • Seizures
  • Signs of stroke — face drooping, one-sided weakness, slurred speech
  • Difficulty breathing; collapse or unconsciousness

What to do

  1. Call emergency services for chest pain, overheating, seizure, or unresponsiveness
  2. Move them to a cool, quiet place and reduce stimulation
  3. Cool the body — remove excess clothing, apply cool damp cloths, fan them
  4. Keep them calm; reassure — panic worsens the cardiovascular strain
  5. If seizing, protect from injury (don't restrain); recovery position afterward
  6. Monitor breathing and be ready to give rescue breaths / CPR

Most stimulant overdoses settle with cooling, a calm environment, and time. The medical danger is hyperthermia, cardiac events (arrhythmia, heart attack, stroke), and seizures — get help immediately if any appear.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/dextroamphetamine · Version r1 · Not medical adviceValues as of
On the printout