Desoxypipradrol Facts
Stimulant;
Description
Desoxypipradrol — also known as 2-DPMP, sold as "Ivory Wave" — is a synthetic stimulant of the piperidine class. It blocks dopamine and norepinephrine clearance in the brain, causing forceful, sustained stimulation.
Subjective effects include wakefulness, appetite suppression, mood elevation, cognitive drive, agitation, and paranoia. The experience is defined by its relentlessness — early clarity gives way to a grinding stimulation that resists sleep for one to three days.
Desoxypipradrol carries high abuse liability and severe acute toxicity — muscle breakdown occurred in 96% of one emergency case series,[1] and deaths have been reported. The extraordinary duration amplifies every risk: a single dose sustains cardiovascular overload for days, and no antidote exists.[2]
Dose and durationby route · individual sensitivity varies
Starts in 1 – 4 hoursLasts 16 – 72 hours
Body and dependence
- Acute toxicity
- High
- Chronic toxicity
- Moderate
- Physical dependence
- Moderate
- Psychological dependence
- High
- Withdrawal
- Moderate
- Compulsive redosing
- High
Tolerance
- Builds
- Moderate
- Fully resets after
- 10.5 days
- Carries over to
- cocaine;
methylphenidate; amphetamine
Effectslikely at a common dose
- Perception
- none likely · 5 possible
- Body
- Stimulation;
Wakefulness; Insomnia; Appetite suppression; Restlessness; Dry mouth; Pupil dilation; +22 possible, including Vasoconstriction, Muscle tension, Heart rate perception changes - Thinking
- none likely · 18 possible, including Compulsive redosing urge, Cognitive dysphoria, Decision impairment
- Feeling
- none likely · 8 possible, including Anxiety, Anhedonia, Depression
- Self
- none likely · 7 possible, including Craving, Ego inflation, Compulsive repetitive behavior
Who shouldn't take it
Combinations61 recorded
Seek help immediately if
- Chest pain; racing, pounding, or irregular heartbeat
- Very high body temperature; heavy sweating; hot, flushed skin
- Severe agitation, paranoia, panic, or confusion
- Severe headache; muscle rigidity or twitching
- Seizures
- Signs of stroke — face drooping, one-sided weakness, slurred speech
- Difficulty breathing; collapse or unconsciousness
What to do
- Call emergency services for chest pain, overheating, seizure, or unresponsiveness
- Move them to a cool, quiet place and reduce stimulation
- Cool the body — remove excess clothing, apply cool damp cloths, fan them
- Keep them calm; reassure — panic worsens the cardiovascular strain
- If seizing, protect from injury (don't restrain); recovery position afterward
- Monitor breathing and be ready to give rescue breaths / CPR
Most stimulant overdoses settle with cooling, a calm environment, and time. The medical danger is hyperthermia, cardiac events (arrhythmia, heart attack, stroke), and seizures — get help immediately if any appear.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
References
- [1]^Murray DB, Potts S, Haxton C, Jackson G, Sandilands EA, Ramsey J, Puchnarewicz M, Holt DW, Johnston A, Bateman DN, Dear JW (2012) 'Ivory wave' toxicity in recreational drug users; integration of clinical and poisons information services to manage legal high poisoning — Clinical Toxicology doi:10.3109/15563650.2011.647992
- [2]^Corkery JM, Elliott S, Schifano F, Corazza O, Ghodse AH (2012) 2-DPMP (desoxypipradrol, 2-benzhydrylpiperidine, 2-phenylmethylpiperidine) and D2PM (diphenyl-2-pyrrolidin-2-yl-methanol, diphenylprolinol): A preliminary review — Progress in Neuro-Psychopharmacology & Biological Psychiatry doi:10.1016/j.pnpbp.2012.05.021