Δ-11-Tetrahydrocannabinol Facts
Cannabinoid;
Dose and duration
No dose or duration recorded for any route.
Body and dependence
- Acute toxicity
- Low
- Chronic toxicity
- Not assessed
- Physical dependence
- Negligible
- Psychological dependence
- Low
- Withdrawal
- None recorded
- Compulsive redosing
- Negligible
Tolerance
- Builds
- Slow
- Fully resets after
- 3 weeks
- Carries over to
- Δ9-THC;
Δ8-THC; other CB1 agonists
Effectslikely at a common dose
- Perception
- none likely · 20 possible, including Spatial disorientation, Vestibular distortion, Visual acuity suppression
- Body
- Body high;
Body scan awareness; Dry mouth; +22 possible, including Heart rate perception changes, Motor control impairment, Dizziness - Thinking
- none likely · 35 possible, including Cognitive impairment, Memory suppression, Decision impairment
- Feeling
- Euphoria;
+8 possible, including Anxiety, Paranoia, Emotional lability - Self
- none likely · 10 possible, including Derealization, Communication suppression, Craving
- Time
- Time alteration;
+3 possible, including Temporal disorientation - Awareness
- none likely · 2 possible
Who shouldn't take it
Absolute
Pregnancy and lactation
Relative
Cardiovascular disease; Psychotic disorders; Concurrent sympathomimetic or epinephrine use
Combinations60 recorded
Dangerous (11)
Ketamine, DXM, PCP; Opioids; GHB, Baclofen; GHB, GBL; Ibogaine; Local anesthetics; MAOIs; NDRIs (Wellbutrin); Salvia, Ibogaine; SNRIs; Synthetic cannabinoids
Caution (34)
See full page: psychedex.org/substances/delta-11-thc
Not graded (15)
Not listed never means safe.
Seek help immediately if
Natural cannabis rarely causes a medical emergency — "greening out" is: pale/sweaty skin, dizziness, nausea or vomiting, anxiety or panic, rapid heartbeat, feeling faint — and usually passes with rest.
Seek emergency help for these — far more likely with synthetic cannabinoids ("spice" / K2):
- Seizures
- Severe chest pain; very fast or irregular heartbeat
- Unresponsiveness or extreme drowsiness
- Severe agitation, aggression, or psychosis
- Repeated vomiting; difficulty breathing
What to do
- Sit or lie them down somewhere calm, cool, and quiet
- Reassure them — cannabis panic and "greening out" pass with time
- Offer sips of water; a little sugar can help if they feel faint
- Recovery position if nauseated, drowsy, or vomiting
- Stay with them and monitor
- For seizures, chest pain, unresponsiveness, or severe agitation, call emergency services
Natural cannabis "greening out" resolves with rest, calm, and time, with no lasting harm. Synthetic cannabinoids are unpredictable and can cause seizures, cardiac events, kidney injury, and severe agitation that needs emergency care.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/delta-11-thc · Version r1 · Not medical adviceValues as of