Sub-classes
AMPA receptor positive allosteric modulatorCompounds that enhance AMPA-type glutamate receptor function by binding to allosteric sites. Proposed to improve synaptic plasticity and memory formation. The putative mechanism of racetam nootropics.Glutamate modulatorCompounds that modulate glutamatergic neurotransmission. A broad category encompassing NMDA and AMPA receptor ligands as well as compounds affecting glutamate release, reuptake, or metabolism.NMDA receptor antagonistCompounds that block NMDA-type glutamate receptors, typically as uncompetitive channel blockers. The primary mechanism producing dissociative effects. Includes ketamine, PCP, MK-801, memantine, and DXM.NMDA receptor modulatorCompounds that modulate NMDA receptor function through mechanisms other than direct channel blockade. Includes glycine site modulators and compounds affecting NMDA receptor trafficking or expression.
Members
–EphenidineDiarylethylamine