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Facts label

Changa Facts

Psychedelic; Substituted tryptamine; Serotonin 2A receptor agonist

Dose and duration

No dose or duration recorded for any route.

Body and dependence

Acute toxicity
Moderate
Chronic toxicity
Low
Physical dependence
None
Psychological dependence
Negligible
Withdrawal
None recorded
Compulsive redosing
Negligible

Tolerance

Builds
None
Fully resets after
1 days
Carries over to
psilocybin; LSD; mescaline

Effectslikely at a common dose

Perception
Geometry; Vestibular distortion; Environmental patterning; Brightness alteration; Color alteration; Color enhancement; Depth perception distortion; Ganzfeld effect; Holotropic state; Perspective distortion; Spatial disorientation; Symmetrical texture repetition; Tracers; Visual breathing; Visual diffraction; Visual drifting; Visual haze / noise; Visual melting; Visual morphing; +16 possible
Body
Body schema distortion; Tingling / electric sensations; Vibrations / buzzing; Spontaneous body sensations; Body high; Wakefulness; Stimulation; Pupil dilation; Dizziness; Heart rate perception changes; Motor control impairment; Body scan awareness; +19 possible, including Nausea, Muscle tension, Excessive sweating
Thinking
Aesthetic enhancement; Cognitive euphoria; Cognitive impairment; Conceptual thinking; Confusion; Decision impairment; Focus suppression; Immersion enhancement; Information processing suppression; Introspection enhancement; Novelty enhancement; Openness enhancement; Pattern recognition enhancement; Thought connectivity; Thought disorganization; +20 possible, including Analysis suppression, Language suppression, Suggestibility enhancement
Feeling
Anxiety; Catharsis; Emotional enhancement; Emotional lability; Euphoria; Simultaneous emotions; +4 possible, including Paranoia, Dysphoria
Self
Derealization; Depersonalization; Communication suppression; Social disconnection; +7 possible
Time
Present-moment absorption; Temporal disorientation; Time alteration; +2 possible
Transpersonal
Unity and interconnectedness
Awareness
Personal insight; +2 possible

Who shouldn't take it

Absolute
Lithium therapy; Psychotic spectrum disorders; Pregnancy; Concurrent SSRIs or SNRIs; Concurrent irreversible MAOIs; Tramadol; Triptans
Relative
Uncontrolled cardiovascular disease; Hepatic impairment; CYP2D6 poor metabolizer phenotype

Combinations60 recorded

Lethal (6)
Amphetamines; MDMA, Amphetamines; MDMA, MDA; Psychedelics; SNRIs; Stimulants
Dangerous (29)
5-HTP, Tryptophan; Alpha-2 adrenergic receptor antagonist; Buspirone; Ephedrine, Pseudoephedrine; Local anesthetics; Opioids; Antihistamines; Antipsychotics; Benzodiazepines, Barbiturates; Caffeine; Cannabis; Clonidine, Guanfacine; Dopamine agonists; DXM; GHB, Baclofen; GHB, GBL; Ibogaine; Ketamine, DXM, PCP; L-Tyrosine; Lithium; Naltrexone; NDRIs (Wellbutrin); NRIs; NSAIDs; and 5 more, see full page
Caution (21)
See full page: psychedex.org/substances/changa
Not graded (4)
Not listed never means safe.

Seek help immediately if

Most difficulty is psychological (intense fear, panic, confusion) and passes with calm support — the signs below mean seek emergency help:

  • Very high body temperature; hot, dry skin
  • Seizures
  • Chest pain; fast or irregular heartbeat
  • Severe muscle rigidity, tremor, or twitching (possible serotonin syndrome)
  • Cold, pale, or blue fingers/toes — severe vasoconstriction (notably NBOMe / DOx)
  • Persistent vomiting; unconsciousness; uncontrollable agitation or risk of self-harm

What to do

  1. Stay calm and reassure — remind them they took a drug and the effect will pass
  2. Move to a calm, quiet, safe space with low light; reduce noise and sensory input
  3. Keep them from harm — they may act on fear or confusion; stay with them, don't leave them alone
  4. Talk them down gently; don't grab or restrain unless they're in danger
  5. For the medical signs above (overheating, seizure, chest pain, vasoconstriction, unresponsive) call emergency services
  6. If overheating, cool the body; be ready to give rescue breaths / CPR

The experience is time-limited and usually resolves with calm reassurance in a safe setting — psychological first aid, not medication. Serious physical harm is uncommon for classic psychedelics (LSD, psilocybin) but real for some potent phenethylamines (NBOMe, DOx), where hyperthermia, seizures, and vasoconstriction warrant emergency care.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/changa · Version r2 · Not medical adviceValues as of
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