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Psychedex
Facts label

CBN Facts

Cannabinoid; Cannabinoid; Cannabinoid CB1 receptor partial agonist

Dose and duration

No dose or duration recorded for any route.

Body and dependence

Acute toxicity
Negligible
Chronic toxicity
Low
Physical dependence
None
Psychological dependence
Negligible
Withdrawal
None recorded
Compulsive redosing
Negligible

Tolerance

Builds
Slow
Fully resets after
Not recorded
Carries over to
Δ⁹-THC

Effectslikely at a common dose

Body
none likely · 10 possible, including Dizziness, Motor control impairment
Thinking
none likely · 5 possible, including Cognitive impairment, Confusion
Feeling
none likely · 2 possible

Who shouldn't take it

Absolute
Pregnancy and lactation
Relative
Severe hepatic impairment; Narrow-TI CYP3A4 substrate medications; Narrow-TI CYP2C9 substrate medications; Driving and machinery operation; Concurrent CNS depressants

Combinations60 recorded

Dangerous (11)
Ketamine, DXM, PCP; Opioids; GHB, Baclofen; GHB, GBL; Ibogaine; Local anesthetics; MAOIs; NDRIs (Wellbutrin); Salvia, Ibogaine; SNRIs; Synthetic cannabinoids
Caution (33)
See full page: psychedex.org/substances/cbn
Not graded (16)
Not listed never means safe.

Seek help immediately if

Natural cannabis rarely causes a medical emergency — "greening out" is: pale/sweaty skin, dizziness, nausea or vomiting, anxiety or panic, rapid heartbeat, feeling faint — and usually passes with rest.

Seek emergency help for these — far more likely with synthetic cannabinoids ("spice" / K2):

  • Seizures
  • Severe chest pain; very fast or irregular heartbeat
  • Unresponsiveness or extreme drowsiness
  • Severe agitation, aggression, or psychosis
  • Repeated vomiting; difficulty breathing

What to do

  1. Sit or lie them down somewhere calm, cool, and quiet
  2. Reassure them — cannabis panic and "greening out" pass with time
  3. Offer sips of water; a little sugar can help if they feel faint
  4. Recovery position if nauseated, drowsy, or vomiting
  5. Stay with them and monitor
  6. For seizures, chest pain, unresponsiveness, or severe agitation, call emergency services

Natural cannabis "greening out" resolves with rest, calm, and time, with no lasting harm. Synthetic cannabinoids are unpredictable and can cause seizures, cardiac events, kidney injury, and severe agitation that needs emergency care.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/cbn · Version r1 · Not medical adviceValues as of
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