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Buspirone Facts

Anxiolytic; Azapirone; Serotonin 1A receptor partial agonist

Dose and durationby route · individual sensitivity varies

Oral(mg)
Threshold< 5 mgLight7.5 – 15 mgCommon15 – 30 mgStrong30 – 60 mgHeavy60+ mg

No duration recorded for this route.

Body and dependence

Acute toxicity
Moderate
Chronic toxicity
Moderate
Physical dependence
Not assessed
Psychological dependence
Not assessed
Withdrawal
Not assessed
Compulsive redosing
Not assessed

Tolerance

Not recorded.

Who shouldn't take it

None recorded. Not listed never means safe to take.

Combinations60 recorded

Dangerous (27)
Anticholinergics; Antihistamines; Benzodiazepines, Barbiturates; GHB, Baclofen; GHB, GBL; Lithium; Opioids; Alpha-2 adrenergic receptor antagonist; Amphetamines; Benzodiazepines; Buprenorphine, Kratom; Clonidine, Guanfacine; Ibogaine; Local anesthetics; MAOIs; MDMA, Amphetamines; MDMA, MDA; Naltrexone; NDRIs (Wellbutrin); NRIs; NSAIDs; Poppers, Nitrates; Salvia, Ibogaine; SNRIs; and 3 more, see full page
Caution (26)
See full page: psychedex.org/substances/buspirone
Not graded (7)
Not listed never means safe.

Seek help immediately if

No emergency profile is recorded for this substance. Not recorded never means no risk.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

Version r1 · Not medical advice
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