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Bromo-DragonFLY Facts

Psychedelic; Substituted phenethylamine; Serotonin 2A receptor agonist

Description

Bromo-DragonFLY (1-(8-bromobenzodifuranyl)-2-aminopropane) is a synthetic psychedelic of the phenethylamine class. It activates serotonin receptors in the brain, producing a multi-day psychedelic state with extreme physical pressure on the body.

Subjective effects include geometric visual patterns, perceptual distortion, altered thinking, and emotional intensification. The experience is defined by a heavy, unrelenting physical component — the heart pounds, blood vessels constrict, and this pressure never lifts for the entire multi-day duration.[1]

Bromo-DragonFLY does not produce physical dependence, but it carries severe acute toxicity — at least five confirmed deaths and no established safe dose.[2] Blood vessel constriction is the primary danger, sustained enough to cause gangrene and limb amputation.[3]

Dose and durationby route · individual sensitivity varies

Oral(µg)
Threshold< 75 µgLight75 – 150 µgCommon150 – 400 µgStrong400 – 750 µgHeavy750+ µg

Starts in 1 – 6 hoursLasts 24 – 96 hoursAfter-effects 12 – 48 hours

Body and dependence

Acute toxicity
Critical
Chronic toxicity
Moderate
Physical dependence
None
Psychological dependence
Negligible
Withdrawal
None recorded
Compulsive redosing
Negligible

Tolerance

Builds
Rapid
Fully resets after
14 days
Carries over to
LSD; psilocybin; mescaline; DOB; DOI; DMT; 2C-B

Effectslikely at a common dose

Perception
Color alteration; Visual drifting; Color enhancement; Geometry; Visual breathing; Visual morphing; Environmental patterning; Light sensitivity; +31 possible, including Visual haze / noise, Spatial disorientation, Vestibular distortion
Body
Pupil dilation; Vasoconstriction; Wakefulness; Insomnia; Stimulation; Physical fatigue; Appetite suppression; +30 possible, including Temperature dysregulation, Muscle tension, Excessive sweating
Thinking
Cognitive fatigue; +31 possible, including Cognitive impairment, Confusion, Thought loops
Feeling
none likely · 10 possible, including Emotional lability, Anxiety, Dysphoria
Self
none likely · 7 possible, including Derealization, Depersonalization, Communication suppression
Time
Time alteration; Temporal disorientation; +3 possible

Who shouldn't take it

Absolute
Peripheral vascular disease; Raynaud's phenomenon; Coronary artery disease; Long QT syndrome; Epilepsy; Psychotic disorders; Bipolar disorder; Pregnancy and lactation; Concurrent serotonergic medications
Relative
Hepatic impairment

Combinations61 recorded

Lethal (1)
MAOIs
Dangerous (18)
MDMA, MDA; NRIs; Buspirone; Dopamine agonists; GHB, Baclofen; GHB, GBL; Ibogaine; Ketamine, DXM, PCP; Lithium; Local anesthetics; MDMA, Amphetamines; NDRIs (Wellbutrin); Psychedelics; Salvia, Ibogaine; SNRIs; SSRIs; Stimulants; Synthetic cannabinoids
Caution (37)
See full page: psychedex.org/substances/bromo-dragonfly
Not graded (5)
Not listed never means safe.

Seek help immediately if

Most difficulty is psychological (intense fear, panic, confusion) and passes with calm support — the signs below mean seek emergency help:

  • Very high body temperature; hot, dry skin
  • Seizures
  • Chest pain; fast or irregular heartbeat
  • Severe muscle rigidity, tremor, or twitching (possible serotonin syndrome)
  • Cold, pale, or blue fingers/toes — severe vasoconstriction (notably NBOMe / DOx)
  • Persistent vomiting; unconsciousness; uncontrollable agitation or risk of self-harm

What to do

  1. Stay calm and reassure — remind them they took a drug and the effect will pass
  2. Move to a calm, quiet, safe space with low light; reduce noise and sensory input
  3. Keep them from harm — they may act on fear or confusion; stay with them, don't leave them alone
  4. Talk them down gently; don't grab or restrain unless they're in danger
  5. For the medical signs above (overheating, seizure, chest pain, vasoconstriction, unresponsive) call emergency services
  6. If overheating, cool the body; be ready to give rescue breaths / CPR

The experience is time-limited and usually resolves with calm reassurance in a safe setting — psychological first aid, not medication. Serious physical harm is uncommon for classic psychedelics (LSD, psilocybin) but real for some potent phenethylamines (NBOMe, DOx), where hyperthermia, seizures, and vasoconstriction warrant emergency care.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

Version r1 · Not medical advice

References

  1. [1]
    ^Noble C, Holm NB, Mardal M, Linnet K (2018) Bromo-dragonfly, a psychoactive benzodifuran, is resistant to hepatic metabolism and potently inhibits monoamine oxidase A — Toxicology Letters doi:10.1016/j.toxlet.2018.07.018
  2. [2]
  3. [3]
    ^Erowid (2007) Bromo-Dragonfly Death and Hospitalization in Sweden (September 2007) Link
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