Bromazepam Facts
Depressant;
Dose and durationby route · individual sensitivity varies
Oral(mg)
Threshold< 1.5 mgLight1.5 – 3 mgCommon3 – 6 mgStrong6 – 12 mgHeavy12+ mg
Starts in 14 – 15 minLasts 6 – 15 hoursAfter-effects 12 – 22 hours
Body and dependence
- Acute toxicity
- Low
- Chronic toxicity
- High
- Physical dependence
- High
- Psychological dependence
- Moderate
- Withdrawal
- Severe · fatal · medical supervision
- Compulsive redosing
- Moderate
Tolerance
- Builds
- Moderate
- Fully resets after
- 3 weeks
- Carries over to
- all benzodiazepines;
alcohol; barbiturates; zolpidem; zopiclone
Effectslikely at a common dose
- Perception
- Dreaming suppression;
+2 possible, including Visual acuity suppression, Vestibular distortion - Body
- Sedation;
Muscle relaxation; +8 possible, including Motor control impairment, Dizziness, Nystagmus (eye wobbles) - Thinking
- none likely · 16 possible, including Memory suppression, Cognitive impairment, Analysis suppression
- Feeling
- Anxiety suppression;
+2 possible - Self
- none likely · 3 possible, including Communication suppression
Who shouldn't take it
Absolute
Severe respiratory depression; Sleep apnea syndrome; Myasthenia gravis; Hypersensitivity to benzodiazepines
Relative
History of substance use disorder; Hepatic impairment; First trimester of pregnancy; Elderly patients (>60 years); Concurrent CNS depressant use
Combinations60 recorded
Lethal (1)
Opioids
Dangerous (21)
Alpha-2 adrenergic receptor antagonist; Antipsychotics; Atypical antipsychotics; Benzodiazepines; Buprenorphine, Kratom; Cannabis, THC; Clonidine, Guanfacine; Gabapentin, Pregabalin; GHB, Baclofen; GHB, GBL; Local anesthetics; Naltrexone; SNRIs; Stimulants; Synthetic cannabinoids; Ibogaine; Ketamine, DXM, PCP; MAOIs; NSAIDs; Poppers (Alkyl nitrites); Poppers, Nitrates
Caution (26)
See full page: psychedex.org/substances/bromazepam
Not graded (12)
Not listed never means safe.
Seek help immediately if
- Extreme drowsiness — can't stay awake or be roused
- Confusion, slurred speech, severe loss of coordination
- Slow, shallow, or irregular breathing
- Unconsciousness / unresponsive; limp, floppy body
- Blue lips or fingertips
- Vomiting while sedated (choking / aspiration risk)
- Cold, clammy skin; weak pulse
What to do
- Try to wake them — shout, firm sternal rub
- If unresponsive or breathing is impaired, call emergency services
- Place them in the recovery position — critical, they can choke on vomit
- Monitor breathing continuously; be ready to give rescue breaths / CPR
- Never leave them alone to "sleep it off"
- Do not give other drugs, stimulants, or more depressants
Most depressant overdoses resolve with airway protection, breathing support, and monitoring. The danger is respiratory depression and choking on vomit — sharply worse when combined with opioids or alcohol. GHB/GBL overdoses often involve sudden deep unconsciousness and may self-resolve, but airway protection is essential.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/bromazepam · Version r1 · Not medical adviceValues as of