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Psychedex
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Benzydamine Facts

Deliriant; Indoleamine; Cyclooxygenase inhibitor

Dose and durationby route · individual sensitivity varies

Oral(mg)
Threshold< 150 mgLight300 – 500 mgCommon500 – 1000 mgStrong1000 – 2000 mgHeavy2000+ mg

Starts in 20 – 60 minLasts 5 – 8 hoursAfter-effects 24 – 72 hours

Body and dependence

Acute toxicity
Not assessed
Chronic toxicity
Not assessed
Physical dependence
Not assessed
Psychological dependence
Not assessed
Withdrawal
Not assessed
Compulsive redosing
Not assessed

Tolerance

Not recorded.

Effectslikely at a common dose

Perception
Geometry; Visual drifting; +5 possible, including Visual haze / noise, Visual acuity suppression
Body
none likely · 4 possible, including Motor control impairment, Dehydration sensation, Dizziness
Thinking
none likely · 2 possible, including Cognitive dysphoria
Feeling
none likely · 2 possible, including Anxiety
Time
none likely · 1 possible

Who shouldn't take it

None recorded. Not listed never means safe to take.

Combinations60 recorded

Lethal (3)
GHB, GBL; Ibogaine; Opioids
Dangerous (38)
Benzodiazepines; Buprenorphine, Kratom; Ephedrine, Pseudoephedrine; Ketamine, DXM, PCP; Lithium; MDMA, Amphetamines; MDMA, MDA; Naltrexone; Nicotine; NRIs; THC; 5-HTP, Tryptophan; Amphetamines; Anticholinergics; Antihistamines; Antipsychotics; Atypical antipsychotics; Benzodiazepines, Barbiturates; Buspirone; Caffeine; Clonidine, Guanfacine; Dopamine agonists; DXM; Gabapentin, Pregabalin; and 14 more, see full page
Caution (15)
See full page: psychedex.org/substances/benzydamine
Not graded (4)
Not listed never means safe.

Seek help immediately if

Deliriants are genuinely dangerous — treat any strong reaction as a medical emergency.

  • True delirium — confused, disoriented, doesn't know what's real or recognize people/danger
  • Vivid, frightening hallucinations; agitation or aggression
  • Hot, flushed, dry skin and high body temperature
  • Dilated pupils; blurred vision
  • Fast heartbeat; inability to urinate
  • Seizures; unconsciousness

What to do

  1. Call emergency services — deliriant poisoning (especially datura / belladonna) can be life-threatening
  2. Keep them physically safe — they may not know what they're doing and can badly injure themselves; remove hazards and stay with them
  3. Do not leave them alone; do not try to reason them out of it — they are delirious
  4. If overheating, cool the body
  5. Recovery position if drowsy, vomiting, or unconscious; be ready for rescue breaths / CPR

Deliriant effects are long (many hours to more than a day) and the person is not safe or in control throughout. The main dangers are self-injury during delirium, overheating, and — for potent anticholinergics like datura — cardiac and central-nervous-system toxicity. Medical monitoring is often needed.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

Version r1 · Not medical advice
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