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AL-LAD Facts

Psychedelic; Lysergamide; Serotonin 2A receptor agonist

Description

AL-LAD (N6-allyl-6-norlysergic acid diethylamide) is a synthetic psychedelic of the lysergamide class. It activates serotonin receptors in the brain, producing the visual and cognitive shifts characteristic of classical psychedelics.[1]

Subjective effects include geometric visual patterns, brightened colors, time alteration, thought acceleration, and mood elevation.[2] The experience is often described as a gentler version of LSD — visually rich and stimulating, but with a softer onset and less demanding peak.

AL-LAD produces no physical dependence, and no lethal dose has been established in any species.[3] The primary risk is psychological — anxiety, panic, or psychosis in predisposed individuals — and tolerance builds so fast that compulsive use is self-limiting.[4]

Dose and durationby route · individual sensitivity varies

Oral(µg)
Threshold< 20 µgLight50 – 100 µgCommon100 – 200 µgStrong200 – 350 µgHeavy350+ µg

Starts in 20 – 60 minLasts 7 – 10 hoursAfter-effects 2 – 18 hours

Body and dependence

Acute toxicity
Negligible
Chronic toxicity
Negligible
Physical dependence
None
Psychological dependence
Negligible
Withdrawal
None recorded
Compulsive redosing
Negligible

Tolerance

Builds
Rapid
Fully resets after
14 days
Carries over to
LSD; psilocybin; mescaline; DMT

Effectslikely at a common dose

Perception
Color enhancement; Visual drifting; Color alteration; Auditory enhancement; Music enhancement; Environmental patterning; Geometry; Visual breathing; Visual morphing; +25 possible, including Spatial disorientation, Visual haze / noise, Vestibular distortion
Body
Wakefulness; Pupil dilation; Spontaneous body sensations; Stimulation; Body high; +29 possible, including Insomnia, Muscle tension, Dizziness
Thinking
Pattern recognition enhancement; Cognitive euphoria; Novelty enhancement; Aesthetic enhancement; Introspection enhancement; +27 possible, including Suggestibility enhancement, Memory suppression, Thought loops
Feeling
Emotional enhancement; Euphoria; +6 possible, including Emotional lability, Anxiety, Paranoia
Self
none likely · 10 possible, including Derealization, Depersonalization, Communication suppression
Time
Time alteration; +4 possible, including Temporal disorientation
Transpersonal
none likely · 1 possible
Awareness
none likely · 4 possible

Who shouldn't take it

Absolute
Psychotic spectrum disorders; Lithium
Relative
Cardiovascular conditions; Anxiety and mood disorders; Pregnancy; Tramadol; MAOIs; SSRIs/SNRIs

Combinations60 recorded

Lethal (1)
MAOIs
Dangerous (19)
Lithium; MDMA, MDA; Buspirone; DXM; GHB, Baclofen; GHB, GBL; Ibogaine; Ketamine, DXM, PCP; Local anesthetics; MDMA, Amphetamines; NDRIs (Wellbutrin); NRIs; NSAIDs; Psychedelics; Salvia, Ibogaine; SNRIs; SSRIs; Stimulants; Synthetic cannabinoids
Caution (35)
See full page: psychedex.org/substances/al-lad
Not graded (5)
Not listed never means safe.

Seek help immediately if

Most difficulty is psychological (intense fear, panic, confusion) and passes with calm support — the signs below mean seek emergency help:

  • Very high body temperature; hot, dry skin
  • Seizures
  • Chest pain; fast or irregular heartbeat
  • Severe muscle rigidity, tremor, or twitching (possible serotonin syndrome)
  • Cold, pale, or blue fingers/toes — severe vasoconstriction (notably NBOMe / DOx)
  • Persistent vomiting; unconsciousness; uncontrollable agitation or risk of self-harm

What to do

  1. Stay calm and reassure — remind them they took a drug and the effect will pass
  2. Move to a calm, quiet, safe space with low light; reduce noise and sensory input
  3. Keep them from harm — they may act on fear or confusion; stay with them, don't leave them alone
  4. Talk them down gently; don't grab or restrain unless they're in danger
  5. For the medical signs above (overheating, seizure, chest pain, vasoconstriction, unresponsive) call emergency services
  6. If overheating, cool the body; be ready to give rescue breaths / CPR

The experience is time-limited and usually resolves with calm reassurance in a safe setting — psychological first aid, not medication. Serious physical harm is uncommon for classic psychedelics (LSD, psilocybin) but real for some potent phenethylamines (NBOMe, DOx), where hyperthermia, seizures, and vasoconstriction warrant emergency care.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

Version r1 · Not medical advice

References

  1. [1]
    ^Brandt SD, Kavanagh PV, Westphal F, Stratford A, Elliott SP, Hoang K, Wallach J, Halberstadt AL (2016) Return of the lysergamides. Part I: Analytical and behavioural characterization of 1-propionyl-d-lysergic acid diethylamide (1P-LSD) — Drug Testing and Analysis doi:10.1002/dta.1884
  2. [2]
    ^Coney LD, Maier LJ, Ferris JA, Winstock AR, Barratt MJ (2017) Genie in a blotter: A comparative study of LSD and LSD analogues' effects and user profile — Human Psychopharmacology doi:10.1002/hup.2599
  3. [3]
    ^Nichols DE (2004) Hallucinogens — Pharmacology & Therapeutics PMID:14761703
  4. [4]
    ^de la Fuente Revenga M, Jaster AM, McGinn J, Silva G, Saha S, Gonzalez-Maeso J (2022) Tolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice — ACS Chemical Neuroscience doi:10.1021/acschemneuro.2c00170
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