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Adrafinil Facts

Stimulant; Eugeroic; Benzhydryl; Dopamine reuptake inhibitor

Dose and durationby route · individual sensitivity varies

Oral(mg)
Threshold< 100 mgLight150 – 250 mgCommon250 – 400 mgStrong400 – 600 mgHeavy600+ mg

Starts in 1 – 2 hoursLasts 6 – 12 hoursAfter-effects 2 – 6 hours

Body and dependence

Acute toxicity
Low
Chronic toxicity
Moderate
Physical dependence
Negligible
Psychological dependence
Low
Withdrawal
None recorded
Compulsive redosing
Low

Tolerance

Builds
Slow
Fully resets after
10.5 days
Carries over to
modafinil; armodafinil; benzhydryl class nootropics

Effectslikely at a common dose

Body
Stimulation; Wakefulness; +8 possible, including Insomnia, Headache, Nausea
Feeling
none likely · 2 possible, including Anxiety
Awareness
Sustained attention (vicara); +1 possible

Who shouldn't take it

Absolute
Hepatic impairment; Known hypersensitivity to modafinil or armodafinil; Pregnancy and breastfeeding; Pediatric use
Relative
Cardiovascular disease; History of psychosis or mania; Concurrent hormonal contraceptive use

Combinations60 recorded

Lethal (1)
Ibogaine
Dangerous (31)
Amphetamines; Benzodiazepines, Barbiturates; Clonidine, Guanfacine; Ephedrine, Pseudoephedrine; GHB, GBL; Local anesthetics; MAOIs; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; Opioids; SNRIs; SSRIs; Stimulants; Anticholinergics; Antipsychotics; Buspirone; Caffeine; Dopamine agonists; DXM; Gabapentin, Pregabalin; GHB, Baclofen; Ketamine, DXM, PCP; and 7 more, see full page
Caution (25)
See full page: psychedex.org/substances/adrafinil
Not graded (3)
Not listed never means safe.

Seek help immediately if

No emergency profile is recorded for this substance. Not recorded never means no risk.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/adrafinil · Version r1 · Not medical adviceValues as of
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