5-MAPB Facts
Stimulant;
Dose and durationby route · individual sensitivity varies
Oral(mg)
Threshold< 20 mgLight40 – 60 mgCommon60 – 80 mgStrong80 – 100 mgHeavy100+ mg
Starts in 20 – 60 minLasts 5 – 8 hoursAfter-effects 6 – 48 hours
Body and dependence
- Acute toxicity
- Low
- Chronic toxicity
- Moderate
- Physical dependence
- Low
- Psychological dependence
- Moderate
- Withdrawal
- Mild
- Compulsive redosing
- Moderate
Tolerance
- Builds
- Moderate
- Fully resets after
- 10 days
- Carries over to
- MDMA;
MDA; 5-APB; 6-APB; 6-MAPB; amphetamine; methamphetamine
Effectslikely at a common dose
- Perception
- Music enhancement;
Touch enhancement; +16 possible, including Visual haze / noise - Body
- Stimulation;
Appetite suppression; Wakefulness; Body high; Body scan awareness; Pupil dilation; Spontaneous body sensations; Tactile euphoria; +27 possible, including Dehydration sensation, Excessive sweating, Nystagmus (eye wobbles) - Thinking
- Cognitive euphoria;
Introspection enhancement; Openness enhancement; +26 possible, including Compulsive redosing urge, Decision impairment, Suggestibility enhancement - Feeling
- Euphoria;
Anxiety suppression; Emotional enhancement; Empathy enhancement; +7 possible, including Emotional lability, Depression, Anhedonia - Self
- Communication enhancement;
Sociability enhancement; Social connection; Trust enhancement; +6 possible, including Compulsive repetitive behavior, Craving - Time
- none likely · 3 possible, including Temporal disorientation
- Transpersonal
- none likely · 1 possible
- Awareness
- none likely · 3 possible
Who shouldn't take it
Absolute
Psychotic disorders; Pregnancy and breastfeeding; MAO inhibitor use; Concurrent serotonergic drug use
Relative
Cardiovascular disease; Bipolar disorder; Hepatic impairment
Combinations61 recorded
Lethal (2)
MAOIs; Tramadol
Dangerous (32)
Alpha-2 adrenergic receptor antagonist; Anticholinergics; Atypical antipsychotics; Caffeine; Dopamine agonists; Ephedrine, Pseudoephedrine; Local anesthetics; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; Opioids; SNRIs; SSRIs; Stimulants; 5-HTP, Tryptophan; Antihistamines; Antipsychotics; Buspirone; Clonidine, Guanfacine; DXM; GHB, Baclofen; GHB, GBL; Ibogaine; and 8 more, see full page
Caution (24)
See full page: psychedex.org/substances/5-mapb
Not graded (3)
Not listed never means safe.
Seek help immediately if
- Overheating / very high body temperature — heavy sweating, then hot dry skin (the leading cause of MDMA deaths, worse when dancing in hot venues)
- Muscle rigidity, jaw clenching, tremor, or twitching (possible serotonin syndrome)
- Fast, pounding heartbeat; chest pain
- Agitation, confusion; seizures
- Hyponatremia (water intoxication) — headache, confusion, drowsiness, vomiting, and seizures from drinking too much water
- Nausea/vomiting; collapse or unconsciousness
What to do
- Move them somewhere cool and help them cool down — overheating is the main danger
- Sip water to stay hydrated but DO NOT overdrink — roughly a cup (250 ml) per hour if active; too much water can be deadly (hyponatremia)
- Get them to rest and stop dancing
- For overheating, seizures, chest pain, muscle rigidity/tremor, confusion, or unresponsiveness, call emergency services
- Recovery position if drowsy or vomiting; stay with them
- Be ready to give rescue breaths / CPR
Most resolve with cooling, rest, sensible hydration, and time. The life-threatening dangers are hyperthermia, serotonin syndrome, and hyponatremia (too much water) — each a medical emergency, not something to wait out.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/5-mapb · Version r1 · Not medical adviceValues as of