3-FA Facts
Stimulant;
Dose and durationby route · individual sensitivity varies
Oral(mg)
Threshold< 10 mgLight20 – 30 mgCommon30 – 50 mgStrong50 – 70 mgHeavy70+ mg
Starts in 20 – 60 minLasts 4 – 6 hoursAfter-effects 2 – 6 hours
Body and dependence
- Acute toxicity
- Moderate
- Chronic toxicity
- Moderate
- Physical dependence
- Moderate
- Psychological dependence
- High
- Withdrawal
- Moderate
- Compulsive redosing
- High
Tolerance
- Builds
- Moderate
- Fully resets after
- 5.5 days
- Carries over to
- amphetamine;
methamphetamine; cocaine; other dopaminergic stimulants
Effectslikely at a common dose
- Perception
- none likely · 5 possible
- Body
- Appetite suppression;
Dry mouth; Insomnia; Pupil dilation; Restlessness; Vasoconstriction; Stimulation; Wakefulness; +19 possible, including Muscle tension, Temperature dysregulation, Excessive sweating - Thinking
- none likely · 16 possible, including Compulsive redosing urge
- Feeling
- Euphoria;
+7 possible, including Anxiety, Dysphoria, Depression - Self
- none likely · 7 possible, including Craving, Ego inflation
Who shouldn't take it
Absolute
Cardiovascular disease; Uncontrolled hypertension; Pregnancy; Concurrent MAOI use
Relative
Seizure disorders; Psychiatric conditions involving psychosis; Hyperthyroidism
Combinations61 recorded
Lethal (2)
MAOIs; Tramadol
Dangerous (33)
Anticholinergics; Atypical antipsychotics; Caffeine; Dopamine agonists; Ephedrine, Pseudoephedrine; Local anesthetics; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; Opioids; Psychedelics; SNRIs; SSRIs; Stimulants; 5-HTP, Tryptophan; Alpha-2 adrenergic receptor antagonist; Antihistamines; Antipsychotics; Buspirone; Clonidine, Guanfacine; DXM; GHB, Baclofen; GHB, GBL; and 9 more, see full page
Caution (23)
See full page: psychedex.org/substances/3-fa
Not graded (3)
Not listed never means safe.
Seek help immediately if
- Chest pain; racing, pounding, or irregular heartbeat
- Very high body temperature; heavy sweating; hot, flushed skin
- Severe agitation, paranoia, panic, or confusion
- Severe headache; muscle rigidity or twitching
- Seizures
- Signs of stroke — face drooping, one-sided weakness, slurred speech
- Difficulty breathing; collapse or unconsciousness
What to do
- Call emergency services for chest pain, overheating, seizure, or unresponsiveness
- Move them to a cool, quiet place and reduce stimulation
- Cool the body — remove excess clothing, apply cool damp cloths, fan them
- Keep them calm; reassure — panic worsens the cardiovascular strain
- If seizing, protect from injury (don't restrain); recovery position afterward
- Monitor breathing and be ready to give rescue breaths / CPR
Most stimulant overdoses settle with cooling, a calm environment, and time. The medical danger is hyperthermia, cardiac events (arrhythmia, heart attack, stroke), and seizures — get help immediately if any appear.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/3-fa · Version r1 · Not medical adviceValues as of