2C-P Facts
Psychedelic;
Dose and durationby route · individual sensitivity varies
Oral(mg)
Threshold< 2 mgLight3 – 5 mgCommon6 – 10 mgStrong10 – 14 mgHeavy16+ mg
Starts in 1 – 3 hoursLasts 10 – 20 hoursAfter-effects 8 – 24 hours
Body and dependence
- Acute toxicity
- Moderate
- Chronic toxicity
- Low
- Physical dependence
- None
- Psychological dependence
- Low
- Withdrawal
- None recorded
- Compulsive redosing
- Negligible
Tolerance
- Builds
- Rapid
- Fully resets after
- 14 days
- Carries over to
- LSD;
psilocybin; mescaline; 2C-B; 2C-E; 2C-I; 2C-D; DOI; DOM
Effectslikely at a common dose
- Perception
- Color enhancement;
Visual drifting; Tracers; Color alteration; Depth perception distortion; After-images; Music enhancement; Symmetrical texture repetition; Brightness alteration; Environmental patterning; Geometry; Holotropic state; Light sensitivity; Perspective distortion; Sleep-transition hallucinations; Visual breathing; Visual morphing; +23 possible, including Spatial disorientation, Visual haze / noise, Vestibular distortion - Body
- Stimulation;
Spontaneous body sensations; Nausea; Pupil dilation; Wakefulness; Body high; Body scan awareness; Insomnia; +29 possible, including Heart rate perception changes, Vasoconstriction, Temperature dysregulation - Thinking
- Introspection enhancement;
Pattern recognition enhancement; Conceptual thinking; Multiple thought streams; Novelty enhancement; Thought loops; Immersion enhancement; Aesthetic enhancement; +27 possible, including Cognitive impairment, Confusion, Decision impairment - Feeling
- Emotional enhancement;
+10 possible, including Anxiety, Emotional lability, Dysphoria - Self
- none likely · 13 possible, including Derealization, Depersonalization, Communication suppression
- Time
- Temporal disorientation;
Time alteration; +3 possible - Transpersonal
- none likely · 1 possible
- Awareness
- Personal insight;
+4 possible
Who shouldn't take it
Absolute
Long QT syndrome; Psychotic disorders; Bipolar disorder; Pregnancy
Relative
Cardiovascular disease; Epilepsy; Hepatic impairment
Combinations61 recorded
Lethal (1)
MAOIs
Dangerous (18)
MDMA, MDA; NRIs; Buspirone; Dopamine agonists; GHB, Baclofen; GHB, GBL; Ibogaine; Ketamine, DXM, PCP; Lithium; Local anesthetics; MDMA, Amphetamines; NDRIs (Wellbutrin); Psychedelics; Salvia, Ibogaine; SNRIs; SSRIs; Stimulants; Synthetic cannabinoids
Caution (37)
See full page: psychedex.org/substances/2c-p
Not graded (5)
Not listed never means safe.
Seek help immediately if
Most difficulty is psychological (intense fear, panic, confusion) and passes with calm support — the signs below mean seek emergency help:
- Very high body temperature; hot, dry skin
- Seizures
- Chest pain; fast or irregular heartbeat
- Severe muscle rigidity, tremor, or twitching (possible serotonin syndrome)
- Cold, pale, or blue fingers/toes — severe vasoconstriction (notably NBOMe / DOx)
- Persistent vomiting; unconsciousness; uncontrollable agitation or risk of self-harm
What to do
- Stay calm and reassure — remind them they took a drug and the effect will pass
- Move to a calm, quiet, safe space with low light; reduce noise and sensory input
- Keep them from harm — they may act on fear or confusion; stay with them, don't leave them alone
- Talk them down gently; don't grab or restrain unless they're in danger
- For the medical signs above (overheating, seizure, chest pain, vasoconstriction, unresponsive) call emergency services
- If overheating, cool the body; be ready to give rescue breaths / CPR
The experience is time-limited and usually resolves with calm reassurance in a safe setting — psychological first aid, not medication. Serious physical harm is uncommon for classic psychedelics (LSD, psilocybin) but real for some potent phenethylamines (NBOMe, DOx), where hyperthermia, seizures, and vasoconstriction warrant emergency care.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/2c-p · Version r1 · Not medical adviceValues as of