2-FMA Facts
Stimulant;
Dose and durationby route · individual sensitivity varies
Oral(mg)
Threshold< 5 mgLight5 – 15 mgCommon15 – 30 mgStrong30 – 50 mgHeavy50+ mg
Starts in 30 – 60 minLasts 7 – 9 hoursAfter-effects 4 – 12 hours
Also recorded: Insufflated. See full page: psychedex.org/substances/2-fma
Body and dependence
- Acute toxicity
- Moderate
- Chronic toxicity
- Moderate
- Physical dependence
- Moderate
- Psychological dependence
- Moderate
- Withdrawal
- Moderate
- Compulsive redosing
- Low
Tolerance
- Builds
- Moderate
- Fully resets after
- 10.5 days
- Carries over to
- amphetamine;
methamphetamine; other dopaminergic stimulants; other fluorinated amphetamines
Effectslikely at a common dose
- Perception
- none likely · 9 possible
- Body
- Pupil dilation;
Vasoconstriction; Appetite suppression; Stimulation; Wakefulness; Insomnia; +24 possible, including Temperature dysregulation, Excessive sweating, Dehydration sensation - Thinking
- none likely · 21 possible, including Compulsive redosing urge
- Feeling
- none likely · 8 possible, including Anxiety, Depression, Anhedonia
- Self
- none likely · 10 possible, including Ego inflation, Craving, Compulsive repetitive behavior
- Awareness
- One-pointedness (ekaggata);
Sustained attention (vicara); +1 possible
Who shouldn't take it
Absolute
Severe cardiovascular disease; MAO inhibitors; Concurrent tramadol use
Relative
Seizure disorders; Psychotic disorders; Hyperthyroidism; Pregnancy and lactation; Narrow-angle glaucoma
Combinations61 recorded
Lethal (2)
MAOIs; Tramadol
Dangerous (28)
Alpha-2 adrenergic receptor antagonist; Anticholinergics; Caffeine; Ephedrine, Pseudoephedrine; GHB, Baclofen; Local anesthetics; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; Opioids; SNRIs; SSRIs; Stimulants; 5-HTP, Tryptophan; Antipsychotics; Buspirone; Dopamine agonists; DXM; GHB, GBL; Ibogaine; Ketamine, DXM, PCP; Lithium; NSAIDs; and 4 more, see full page
Caution (28)
See full page: psychedex.org/substances/2-fma
Not graded (3)
Not listed never means safe.
Seek help immediately if
- Chest pain; racing, pounding, or irregular heartbeat
- Very high body temperature; heavy sweating; hot, flushed skin
- Severe agitation, paranoia, panic, or confusion
- Severe headache; muscle rigidity or twitching
- Seizures
- Signs of stroke — face drooping, one-sided weakness, slurred speech
- Difficulty breathing; collapse or unconsciousness
What to do
- Call emergency services for chest pain, overheating, seizure, or unresponsiveness
- Move them to a cool, quiet place and reduce stimulation
- Cool the body — remove excess clothing, apply cool damp cloths, fan them
- Keep them calm; reassure — panic worsens the cardiovascular strain
- If seizing, protect from injury (don't restrain); recovery position afterward
- Monitor breathing and be ready to give rescue breaths / CPR
Most stimulant overdoses settle with cooling, a calm environment, and time. The medical danger is hyperthermia, cardiac events (arrhythmia, heart attack, stroke), and seizures — get help immediately if any appear.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/2-fma · Version r1.a1 · Not medical adviceValues as of