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2-FMA Facts

Stimulant; Substituted amphetamine; Monoamine releasing agent

Dose and durationby route · individual sensitivity varies

Oral(mg)
Threshold< 5 mgLight5 – 15 mgCommon15 – 30 mgStrong30 – 50 mgHeavy50+ mg

Starts in 30 – 60 minLasts 7 – 9 hoursAfter-effects 4 – 12 hours

Also recorded: Insufflated. See full page: psychedex.org/substances/2-fma

Body and dependence

Acute toxicity
Moderate
Chronic toxicity
Moderate
Physical dependence
Moderate
Psychological dependence
Moderate
Withdrawal
Moderate
Compulsive redosing
Low

Tolerance

Builds
Moderate
Fully resets after
10.5 days
Carries over to
amphetamine; methamphetamine; other dopaminergic stimulants; other fluorinated amphetamines

Effectslikely at a common dose

Body
Pupil dilation; Vasoconstriction; Appetite suppression; Stimulation; Wakefulness; Insomnia; +24 possible, including Temperature dysregulation, Excessive sweating, Dehydration sensation
Thinking
none likely · 21 possible, including Compulsive redosing urge
Feeling
none likely · 8 possible, including Anxiety, Depression, Anhedonia
Self
none likely · 10 possible, including Ego inflation, Craving, Compulsive repetitive behavior
Awareness
One-pointedness (ekaggata); Sustained attention (vicara); +1 possible

Who shouldn't take it

Absolute
Severe cardiovascular disease; MAO inhibitors; Concurrent tramadol use
Relative
Seizure disorders; Psychotic disorders; Hyperthyroidism; Pregnancy and lactation; Narrow-angle glaucoma

Combinations61 recorded

Lethal (2)
MAOIs; Tramadol
Dangerous (28)
Alpha-2 adrenergic receptor antagonist; Anticholinergics; Caffeine; Ephedrine, Pseudoephedrine; GHB, Baclofen; Local anesthetics; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; Opioids; SNRIs; SSRIs; Stimulants; 5-HTP, Tryptophan; Antipsychotics; Buspirone; Dopamine agonists; DXM; GHB, GBL; Ibogaine; Ketamine, DXM, PCP; Lithium; NSAIDs; and 4 more, see full page
Caution (28)
See full page: psychedex.org/substances/2-fma
Not graded (3)
Not listed never means safe.

Seek help immediately if

  • Chest pain; racing, pounding, or irregular heartbeat
  • Very high body temperature; heavy sweating; hot, flushed skin
  • Severe agitation, paranoia, panic, or confusion
  • Severe headache; muscle rigidity or twitching
  • Seizures
  • Signs of stroke — face drooping, one-sided weakness, slurred speech
  • Difficulty breathing; collapse or unconsciousness

What to do

  1. Call emergency services for chest pain, overheating, seizure, or unresponsiveness
  2. Move them to a cool, quiet place and reduce stimulation
  3. Cool the body — remove excess clothing, apply cool damp cloths, fan them
  4. Keep them calm; reassure — panic worsens the cardiovascular strain
  5. If seizing, protect from injury (don't restrain); recovery position afterward
  6. Monitor breathing and be ready to give rescue breaths / CPR

Most stimulant overdoses settle with cooling, a calm environment, and time. The medical danger is hyperthermia, cardiac events (arrhythmia, heart attack, stroke), and seizures — get help immediately if any appear.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/2-fma · Version r1.a1 · Not medical adviceValues as of
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