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1BP-LSD Facts

Psychedelic; Lysergamide; Serotonin 2A receptor agonist

Description

1BP-LSD (1-boronobenzoyl-lysergic acid diethylamide) is a synthetic psychedelic of the lysergamide class. It activates serotonin receptors in the brain, producing the visual and cognitive shifts characteristic of classical psychedelics.[1]

Subjective effects include geometric visual patterns, brightened colors, thought connectivity, emotional intensification, and ego dissolution. The experience mirrors LSD — expansive, stimulant-edged, and mentally sharp — but arrives through a slow come-up that can stretch two or more hours.[2]

1BP-LSD produces no physical dependence, and no death has been attributed to its active metabolite LSD.[3] The primary danger is psychological — high doses in unsupported settings can trigger acute panic, and people with a personal or family history of psychosis face disproportionate risk of lasting destabilization.[4]

Dose and durationby route · individual sensitivity varies

Oral(µg)
Threshold< 50 µgLight75 – 125 µgCommon150 – 200 µgStrong225 – 350 µgHeavy375+ µg

Starts in 60 – 120 minLasts 10 – 14 hoursAfter-effects 12 – 48 hours

Body and dependence

Acute toxicity
Low
Chronic toxicity
Low
Physical dependence
None
Psychological dependence
Negligible
Withdrawal
None recorded
Compulsive redosing
Negligible

Tolerance

Builds
Rapid
Fully resets after
10 days
Carries over to
LSD; psilocybin; DMT; mescaline; 1P-LSD; 1B-LSD; 1cP-LSD; 1V-LSD; 1S-LSD

Effectslikely at a common dose

Perception
Color alteration; Color enhancement; Geometry; Music enhancement; Visual breathing; Visual drifting; +33 possible, including Spatial disorientation, Vestibular distortion, Visual haze / noise
Body
Body scan awareness; Insomnia; Pupil dilation; Stimulation; Wakefulness; +31 possible, including Heart rate perception changes, Muscle tension, Dizziness
Thinking
Aesthetic enhancement; Introspection enhancement; Openness enhancement; +34 possible, including Decision impairment, Suggestibility enhancement, Thought loops
Feeling
Emotional enhancement; +10 possible, including Emotional lability, Anxiety, Paranoia
Self
none likely · 12 possible, including Derealization, Depersonalization, Ego inflation
Time
Time alteration; +4 possible, including Temporal disorientation
Transpersonal
none likely · 1 possible
Awareness
none likely · 6 possible

Who shouldn't take it

Absolute
Psychotic disorders; Lithium; MAOIs
Relative
Cardiovascular disease; Seizure disorders; Bipolar disorder with psychotic features; Pregnancy and breastfeeding; Mood stabilizers

Combinations61 recorded

Lethal (1)
MAOIs
Dangerous (18)
MDMA, MDA; NRIs; Buspirone; Dopamine agonists; GHB, Baclofen; GHB, GBL; Ibogaine; Ketamine, DXM, PCP; Lithium; Local anesthetics; MDMA, Amphetamines; NDRIs (Wellbutrin); Psychedelics; Salvia, Ibogaine; SNRIs; SSRIs; Stimulants; Synthetic cannabinoids
Caution (37)
See full page: psychedex.org/substances/1bp-lsd
Not graded (5)
Not listed never means safe.

Seek help immediately if

Most difficulty is psychological (intense fear, panic, confusion) and passes with calm support — the signs below mean seek emergency help:

  • Very high body temperature; hot, dry skin
  • Seizures
  • Chest pain; fast or irregular heartbeat
  • Severe muscle rigidity, tremor, or twitching (possible serotonin syndrome)
  • Cold, pale, or blue fingers/toes — severe vasoconstriction (notably NBOMe / DOx)
  • Persistent vomiting; unconsciousness; uncontrollable agitation or risk of self-harm

What to do

  1. Stay calm and reassure — remind them they took a drug and the effect will pass
  2. Move to a calm, quiet, safe space with low light; reduce noise and sensory input
  3. Keep them from harm — they may act on fear or confusion; stay with them, don't leave them alone
  4. Talk them down gently; don't grab or restrain unless they're in danger
  5. For the medical signs above (overheating, seizure, chest pain, vasoconstriction, unresponsive) call emergency services
  6. If overheating, cool the body; be ready to give rescue breaths / CPR

The experience is time-limited and usually resolves with calm reassurance in a safe setting — psychological first aid, not medication. Serious physical harm is uncommon for classic psychedelics (LSD, psilocybin) but real for some potent phenethylamines (NBOMe, DOx), where hyperthermia, seizures, and vasoconstriction warrant emergency care.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

Version r1 · Not medical advice

References

  1. [1]
    ^Holze F, Vizeli P, Müller F, Ley L, Duerig R, Varghese N, Zizzari P, Liechti ME (2021) Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects — Neuropsychopharmacology doi:10.1038/s41386-020-00883-6
  2. [2]
    ^ModernMind.eu (2026) 1BP-LSD vs 1FE-LSD: Analysis of these new lysergamides Link
  3. [3]
    ^StatPearls (NCBI Bookshelf) (2024) Lysergic Acid Diethylamide Toxicity Link
  4. [4]
    ^Schlag AK, Aday J, Salam I, Neill JC, Nutt DJ (2022) Adverse effects of psychedelics: From anecdotes and misinformation to systematic science — Journal of Psychopharmacology doi:10.1177/02698811211069100
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